Active Recombinant Mouse Met Proto-Oncogene, Fc-tagged
Cat.No. : | Met-730M |
Product Overview : | Recombinant Mouse Metprotein was expressed in Murine myeloma cell line with the Fc part of MouseIgG2A Glu98-Lys330 (C-terminus) and Met1-Asn929 (N-terminus). |
- Specification
- Gene Information
- Related Products
Cat. No. : | Met-730M |
Description : | Met is aglycosylated receptor tyrosine kinase that plays a central role in epithelialmorphogenesis and cancer development. Met is synthesized as a single chainprecursor which undergoes cotranslational proteolytic cleavage. This generatesa mature Met that is a disulfide-linked dimer composed of a 50 kDaextracellular α chain and a 145 kDa transmembrane β chain. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in PBS. |
N-terminalSequence : | Glu25 & Ser307 |
Molecular Weight : | 96 &32 kDa |
Activity : | Measuredby its ability to bind recombinant mouse Met in a functional ELISA with anestimated KD < 0.2 nM. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
SDS-PAGE : | 110-120kDa & 40-43 kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 200 μg/ mLin PBS |
Storage : | Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8 °C under sterile conditionsafter reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | Met met proto-oncogene [ Musmusculus ] |
Official Symbol : | Met |
Synonyms : | Met; metproto-oncogene; HGF; HGFR; Par4; c-Met; AI838057; hepatocyte growth factorreceptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met;scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogenetyrosine kinase; EC 2.7.10.1; Met protein |
Gene ID : | 17295 |
mRNA Refseq : | NM_008591 |
Protein Refseq : | NP_032617 |
UniProt ID : | P16056 |
Chromosome Location : | 6 A2; 6 4.0 cM |
Pathway : | Adherens junction;Alpha6-Beta4 Integrin Signaling Pathway; Axon guidance; Bacterial invasion ofepithelial cells; Cytokine-cytokine receptor interaction; DevelopmentalBiology; Endocytosis; Focal Adhesion; Focal adhesion; Malaria; Melanoma;Pathways in cancer; Renal cell carcinoma; Sema4D in semaphorin signaling;Semaphorin interactions |
Function : | ATP binding;beta-catenin binding; hepatocyte growth factor-activated receptor activity;kinase activity; nucleotide binding; phosphatidylinositol 3-kinase binding;phospholipase binding; protein complex binding; protein heterodimerizationactivity; protein kinase activity; protein tyrosine kinase activity; receptoractivity; transferase activity |
Products Types
◆ Lysates | ||
MET-2529HCL | Recombinant Human MET cell lysate | +Inquiry |
MET-001HCL | Recombinant Human MET cell lysate | +Inquiry |
MET-001CCL | Recombinant Cynomolgus MET cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0550 | Met Kinase (Human) Assay/Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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