Active Recombinant Rat periostin Protein, His tagged

• Cat.No.: Postn-05R
• Product Overview: Active Recombinant Rat Postn Protein (Asn24-Ser800) with a C-terminal 6-His tag was expressed in Human embryonic kidney cell.

Specification

• Species: Rat
• Source: HEK293
• Tag: His
• Protein Length: 24-800 aa
• Description: Predicted to enable cell adhesion molecule binding activity; heparin binding activity; and metal ion binding activity. Involved in several processes, including bone regeneration; negative regulation of cell-substrate adhesion; and positive regulation of chemokine (C-X-C motif) ligand 2 production. Located in extracellular space and neuromuscular junction. Used to study congestive heart failure. Biomarker of artery disease (multiple); degenerative disc disease; end stage renal disease; periodontitis; and tendinitis. Orthologous to human POSTN (periostin).
• Tag: C-6×His
• Molecular Mass: 87 kDa
• N-terminal Sequence Analysis: Asn24
• Bio-Activity: Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.6-3.6 μg/mL.
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in MES, NaCl and Brij-35.
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.
• Reference: 1. Liu, A.Y. et al. (2014) Matrix Biol. 37:150.
  2. Gillan, L. et al. (2002) Cancer Res. 62:5358.
  3. Takeshita, S. et al. (1993) Biochem. J. 294:271.

Gene Information

• Gene Name: Postn periostin [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Postn
• Synonyms: Postn; periostin; Plf; periostin; periostin, osteoblast specific factor; periostin-like factor
• Gene ID: 361945
• mRNA Refseq: NM_001108550
• Protein Refseq: NP_001102020
• UniProt ID: D3ZAF5