Active Recombinant Rhesus Macaque IL23R protein, hFc-tagged
Cat.No. : | IL23R-804R |
Product Overview : | Recombinant Rhesus Macaque IL23R protein (F6XR82) (Met1-Asp353) was expressed in HEK293, fused with the Fc region of human IgG1 at the C-terminus. |
- Specification
- Gene Information
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Source : | HEK293 |
Species : | Rhesus Macaque |
Tag : | hFc |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its binding ability in a functional ELISA. 1. Immobilized human IL23A-His+IL12B-His at 10 μg/ml (100 μl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.14-0.35 μg/ml. 2.Immobilized mouse mIL12Bh (m)+mIL23Ah at 10 μg/ml (100 μl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.05-0.11 μg/ml. |
Molecular Mass : | The recombinant cynomolgus / rhesus IL23R comprises 571 amino acids and has a calculated molecular mass of 64.9 KDa. |
Protein length : | Met1-Asp353 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended to reconstitute the lyophilized powder in sterile water to 100-200 ug/ml, and further dilute with other solvents. The dissolved protein can be stored at 4°C for 2-7 days and should be used up as soon as possible. If not in use for a short time, please store at -20°C. |
Gene Name : | IL23R interleukin 23 receptor [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | IL23R |
Synonyms : | IL23R |
Gene ID : | 700440 |
mRNA Refseq : | XM_028832665.1 |
Protein Refseq : | XP_028688498.1 |
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Il23r-8801R | Active Recombinant Rat Il23r protein(Met1-Asp367), hFc-tagged | +Inquiry |
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◆ Lysates | ||
IL23R-1429CCL | Recombinant Cynomolgus IL23R cell lysate | +Inquiry |
IL23R-1213HCL | Recombinant Human IL23R cell lysate | +Inquiry |
IL23R-1234RCL | Recombinant Rat IL23R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIL23R activation promotes Th17 cell differentiation.
IL23R has multiple alternative splicing variants.
IL23R undergoes phosphorylation that affects its stability.
The half-life of IL23R protein in activated T-cells is approximately 48 hours.
MicroRNAs like miR-20a regulate IL23R expression.
IL23R contributes to the release of pro-inflammatory cytokines like IL-17.
IL23R is implicated in autoimmune diseases like Crohn's.
IL23R expression is upregulated during bacterial infection.
IL23R forms heterodimers with IL-12Rβ1.
IL23R activates the JAK-STAT and NF-κB pathways.
Customer Reviews (3)
Write a reviewHigh specificity in ELISA.
Effective in autoimmune models.
Suitable for receptor binding studies.
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