Active Recombinant Human IL23R protein, mFc-tagged, Low Endotoxin

• Cat.No.: IL23R-614H
• Product Overview: Recombinant Human IL23R protein(Q5VWK5-1)(Gly24-Gly355), fused with C-terminal mFc tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: mFc
• Protein Length: 24-355 aa
• Form: Lyophilized from 0.22μm filtered solution in PBS, 10% trehalose (pH 7.4).
• Bio-activity: Immobilized Biotinylated Human IL-23 alpha&IL-12 beta, His Tag at 5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Human IL-23R, mFc Tag with the EC50 of 36.4ng/ml determined by ELISA.
• Molecular Mass: The protein has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.01 EU per μg by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 85% as determined by HPLC
• Storage: Store at -20 to -80°C for 24 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
• Reconstitution: Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: IL23R interleukin 23 receptor [ Homo sapiens ]
• Official Symbol: IL23R
• Synonyms: IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor
• Gene ID: 149233
• mRNA Refseq: NM_144701
• Protein Refseq: NP_653302
• MIM: 607562
• UniProt ID: Q5VWK5