Bisphosphoglycerate mutase

• Cat.No.: CBCRY13

Specification

• Source: E.coli
• Tag: Non
• Background: Bisphosphoglycerate mutase is an erythrocyte-specific enzyme catalyzing a series of intermolecular phosphoryl group transfer reactions. Its main function is to synthesize 2,3-bisphosphoglycerate, the allosteric effector of hemoglobin.
• Protein Classification: Isomerase
• Structure Weight: 63399.57 Da
• Polymer: 1
• Molecule: Bisphosphoglycerate mutase
• Chain Length: 271 amino acids
• PDB ID: 2HHJ
• MMDB ID: 53343
• Method: X-Ray Diffraction
• Resolution: 1.5Å
• Ligand Chemical Component: 3-phosphoglyceric acid; 2,3-diphosphoglyceric acid; cyclohexylammonium ion
• Reference: Wang, Y., Liu, L., Wei, Z., Cheng, Z., Lin, Y., Gong, W.(2006) Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase.J.Biol.Chem.281: 39642-39648

Gene Information

• Gene Name: BPGM
• Synonyms: EC 5.4.2.4; EC 5.4.2.1; EC 3.1.3.13; 2,3-bisphosphoglycerate mutase; 2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase; BPG-dependent PGAM
• UniProt ID: P07738
• Gene ID: 669
• Chromosome Location: 7q31-q34
• Function: bisphosphoglycerate 2-phosphatase activity; bisphosphoglycerate mutase activity; hydrolase activity; isomerase activity; phosphoglycerate mutase activity; intramolecular transferase activity; phosphatrasferase