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                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Caspase-5 Inhibitor Drug Screening Kit (Fluorometric)

Cat.No. : Kit-2333
Product Overview : Caspases have been shown to play a crucial role in apoptosis induced by various deleterious and physiologic stimuli. Inhibition of caspases can delay apoptosis, implicating a potential role in drug screening efforts. The Caspase-5 Inhibitor Drug Screening Kit provides an effective means for screening caspase inhibitors using fluorometric methods. The assay utilizes synthetic peptide substrate WEHD-AFC (AFC, 7-amino-4-trifluoromethyl coumarin). Active caspase-5 cleaves the synthetic substrate to release free AFC which can then be quantified by fluorometry. Compounds to be screened can directly be added to the reaction and the level of inhibition of caspase-5 activity can be determined by comparison of the fluorescence intensity in samples with and without the testing inhibitors.
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Applications : Effective means for screening caspase inhibitors using fluorometric methods.
Storage : -20°C
Size : 100 assays

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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