CD19 protein-coupled magnetic MicroBeads

Species :	Human
Capacity :	for 1×10^9 total cells
Background :	As a B cell lineage marker, the CD19 antigen is expressed from the early pro-B cell stage to the B cell lymphoblast stage, but the expression is down-regulated upon B cell maturation to plasma cells. The CD19 antigen is further expressed on most malignant B cells and on a subset of follicular dendritic cells.
Application :	Isolated CD19+ B cells were used for studies on immunoglobulin production, such as IgE synthesis and secretion, chemotaxis assays, or mixed lymphocyte reactions. Positively selected CD19+ B cells were also used for molecular studies such as gene expression profiling. For the analysis of minimal residual diseases in B cell malignancies, enrichment of B cells increases the sensitivity of detection.