Chloride Channel Assay Kit

• Cat.No.: Kit-0217
• Product Overview: Chloride Channel Assay Kit is used for the measurement of chloride channel activity.

Specification

• Tag: Non
• Description: Chloride channels have a variety of important physiological and cellular functions that include regulation of pH, volume homeostasis, organic solute transport, cell migration, cell proliferation and differentiation. Chloride channels represent valuable drug targets. A number of chronic disease states such as cystic fibrosis and Bartters syndrome are due to defects in chloride channel functions. However, the existing technologies for screening chloride channel modulators are a compromise between throughput, sensitivity and physiological relevance.
• Usage: For research use only (RUO)
• Storage: Keep in -20°CProtect from moisture and lightAvoid repeated freeze-thaw cycles
• Kit Components: Component A: Iodide Blue Sensor 50 mlComponent B: Iodide Sensor Enhancer (100X) 0.5 mlComponent C: ILoadingBuffer 100 mlComponent D: Cell Lysis Buffer (10X) 5 ml
• Detection method: Colorimetric
• Compatible Sample Types: Live Cells
• Features & Benefits: High Sensitivity: As low as 30 nM of iodide can be detected.Convenient: Formulated to have minimal hands-on time.Less toxicity: Ease of use with less toxicity than the classic Sandell and Kolthoff assay.Continuous: Continuous assay without a separation step.