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Recombinant Human Wolf-Hirschhorn Syndrome Candidate 2, T7-tagged

Cat.No. : WHSC2-3015H
Product Overview : Recombinant Human WHSC2 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 57349 Da(525 aa).
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  • Gene Information
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Cat. No. : WHSC2-3015H
Description : Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. WHSC2 encodes the NELF-A subunit of the NELF complex.
Sequences of amino acids : 1-525 aa
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
Purity : 90%
Gene Name : WHSC2 Wolf-Hirschhorn syndrome candidate 2 [ Homo sapiens ]
Synonyms : Wolf-Hirschhorn syndrome candidate 2;NELFA; NELF-A; FLJ10442; FLJ25112; P/OKcl.15; WHSC2; negative elongation factor A; OTTHUMP00000211580
Gene ID : 7469
mRNA Refseq : NM_005663
Protein Refseq : NP_005654
MIM : 606026
UniProt ID : Q9H3P2
Chromosome Location : 4p16.3
Pathway : Gene Expression; HIV Infection; Transcription

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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