"PDXP" Related Products

Recombinant Human PDXP, His-tagged

Cat. No.: PDXP-2762H
Product Overview: Recombinant human PDXP protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.
Description: Pyridoxal phosphate phosphatase, also known as PDXP is the enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. PDXP catalyzes the dephosphorylation of pyridoxal 5"-phosphate and exhibits a high level of expression various parts of the central nervous system, especially the brain. PDXP activity is catalyzed by haloacid dehalogenase (HAD), and it is the cofactor of both aromatic L-amino acid decarboxylase and glutamate decarboxylase.
Source: E.coli.
Purity: > 95% by SDS – PAGE.
Sequences: MGSSHHHHHH SSGLVPRGSH MARCERLRGA ALRDVLGRAQ GVLFDCDGVL WNGERAVPGA PELLERLARA GKAALFVSNN SRRARPELAL RFARLGFGGL RAEQLFSSAL CAARLLRQRL PGPPDAPGAV FVLGGEGLRA ELRAAGLRLA GDPSAGDGAA PRVRAVLVGY DEHFSFAKLR EACAHLRDPE CLLVATDRDP WHPLSDGSRT PGTGSLAAAV ETASGRQALV VGKPSPYMFE CITENFSIDP ARTLMVGDRL ETDILFGHRC GMTTVLTLTG VSRLEEAQAY LAAGQHDLVP HYYVESIADL TEGLED.
Molecular Weight: 33.8 kDa (316aa) confirmed by MALDI-TOF.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,20% glycerol, 0.1M NaCl.
Concentration: 1 mg/ml (determined by Bradford assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase [ Homo sapiens ]
Synonyms:
PDXP; pyridoxal (pyridoxine, vitamin B6) phosphatase; PLP phosphatase; chronophin; pyridoxal phosphate phosphatase; CIN; PLP; FLJ32703; dJ37E16.5; EC 3.1.3.74
Gene ID: 57026
mRNA Refseq: NM_020315
Protein Refseq: NP_064711
MIM: 609246
UniProt ID: Q96GD0
Chromosome Location: 22cen-q12.3
Pathway: Metabolic pathways; Vitamin B6 metabolism
Function: heat shock protein binding; hydrolase activity; metal ion binding; phosphoprotein phosphatase activity; pyridoxal phosphatase activity

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