"BAG2" Related Products

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Recombinant Human BAG2, His-tagged

Cat. No. : BAG2-3406H
Product Overview : Recombinant human BAG2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description : BCL2-associated athanogene 2, also known as BAG2, is a member of the Bag family of proteins. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain. BAG2 is a major component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex and acts to disrupt CHIP-mediated ubiquitylation.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl.
Molecular Weight : 25.9 kDa (231aa) confirmed by MALDI-TOF.
Purity : > 95% by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLD QLELRVE ALREAATAVE QEKEILLEMI HSIQNSQDMRQISDGEREEL NLTA NRLM GR TLTVEVSVET IRNPQQQESL KHATRIIDEV VNKFLDDLGN AKSHLMSLYS ACS SEVPHGP VDQKFQSIVI GCALEDQKKI KRRLETLLRN IENSDKAIKL LEH SKG AG SK TLQQNAESRF N.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Protein processing in endoplasmic reticulum
Gene Name : BAG2 BCL2-associated athanogene 2 [ Homo sapiens ]
Synonyms : BCL2-associated athanogene 2; BAG-2; KIAA0576; MGC149462; dJ417I1.2; BAG2; BAG family molecular chaperone regulator 2; bcl-2-associated athanogene 2; BAG-family molecular chaperone regulator-2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); Bcl-2-associated athanogene 2
Gene ID : 9532
mRNA Refseq : NM_004282
Protein Refseq : NP_004273
MIM : 603882
UniProt ID : O95816
Chromosome Location : 6p12.1-p11.2
Function : protein binding

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