Recombinant Human Bleomycin Hydrolase, His-tagged
Cat.No. : | BLMH-802H |
Product Overview : | Recombinant human BLMH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. MW = 54.7 kDa(475aa), confirmed by MALDI-TOF. |
- Specification
- Gene Information
- Related Products
Cat. No. : | BLMH-802H |
Description : | BLMH is a member of the papain superfamily of the cysteine protease and the peptidase C1 family. It is a cytoplasmic cysteinepeptidase commonly found as a homohexamer.The normal physiological role of BLMH is unknown, but it protects normal and malignant cells from the glycopeptide antitumor drug BLM. It catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxyamide bond of its B-aminoalaninamide moiety and also shows general aminopeptidase activity. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MSSSGLNSEK VAALIQKLNS DPQFVLAQNV GTTHDLLDIC LKRATVQRAQ HVFQHAVPQE GKPITNQKSS GRCWIFSCLN VMRLPFMKKL NIEEFEFSQS YLFFWDKVER CYFFLSAFVD TAQRKEPEDG RLVQFLLMNP ANDGGQWDML VNIVEKYGVI PKKCFPESYT TEATRRMNDI LNHKMREFCI RLRNLVHSGA TKGEISATQD VMMEEIFRVV CICLGNPPET FTWEYRDKDK NYQKIGPITP LEFYREHVKP LFNMEDKICL VNDPRPQHKY NKLYTVEYLS NMVGGRKTLY NNQPIDFLKK MVAASIKDGE AVWFGCDVGK HFNSKLGLSD MNLYDHELVF GVSLKNMNKA ERLTFGESLM THAMTFTAVS EKDDQDGAFT KWRVENSWGE DHGHKGYLCM TDEWFSEYVY EVVVDRKHVP EEVLAVLEQE PIILPAWDPM GALAE |
Purity : | > 90% by SDS – PAGE. |
Form : | Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | BLMH bleomycin hydrolase [ Homo sapiens ] |
Synonyms : | BLMH; bleomycin hydrolase; BH; BMH; BLM hydrolase; EC 3.4.22.40 |
Gene ID : | 642 |
mRNA Refseq : | NM_000386 |
Protein Refseq : | NP_000377 |
MIM : | 602403 |
UniProt ID : | Q13867 |
Chromosome Location : | 17q11.2 |
Function : | aminopeptidase activity; carboxypeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
Blmh-419M | Recombinant Mouse Blmh Protein, His-tagged | +Inquiry |
BLMH-418H | Recombinant Human BLMH Protein, His-tagged | +Inquiry |
Blmh-420R | Recombinant Rat Blmh Protein, His-tagged | +Inquiry |
BLMH-1041M | Recombinant Mouse BLMH Protein, His (Fc)-Avi-tagged | +Inquiry |
BLMH-242H | Recombinant Human BLMH Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
BLMH-8445HCL | Recombinant Human BLMH 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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