Recombinant Human Chemokine (C-C motif) Ligand 4-Like 1

• Cat.No.: CCL4L1-332H
• Product Overview: Recombinant humanCCL4L1 protein was expressed in E. coli and purified by conventionalchromatography.

Specification

• Cat. No.: CCL4L1-332H
• Description: LAG-1 is CCchemokine that signals through the CCR5 receptor. CCL4L1 is identical toMIP-1beta (ACT II isotype) except for two amino acid substitutions; argininefor histidine at position 22 and serine for glycine at position 47 of themature protein. CCL4L1 chemoattracts monocytes, and exhibits activity as anHIV suppressive factor.
• Source: Human
• Host: E. coli
• Form: Supplied as a liquidin 10 mM sodium citrate, pH 3.5, containing 10% glycerol.
• Purity: > 98% by SDS-PAGEand HPLC
• Sequence: Region of CCL4L1protein corresponding to amino acids APMGSDPPTA CCFSYTARKL PRNFVVDYYETSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN.
• Molecular Mass: 7.7 kDa
• Storage: Store at 4 deg Cuntil reconstitution. Following reconstitution aliquot and freeze at -20 degC for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: CCL4L1

Gene Information

• Gene Name: CCL4L1 chemokine (C-C motif) ligand 4-like1 [ Homo sapiens ]
• Synonyms: CCL4L1; chemokine(C-C motif) ligand 4-like 1; LAG1; CCL4L; LAG-1; SCYA4L; AT744.2; chemokine(C-C motif) ligand 4-like; small inducible cytokine A4-like; C-C motifchemokine 4-like; Lymphocyte activation gene 1 protein; Macrophageinflammatory protein 1-beta; MIP-1-beta; Monocyte adherence-induced protein5-alpha; Small-inducible cytokine A4-like; SCYA4L1; SCYA4L2; CCL4L2
• Gene ID: 9560
• mRNA Refseq: NM_001001435
• Protein Refseq: NP_001001435
• MIM: 603782
• UniProt ID: P13236
• Chromosome Location: 17q12
• Pathway: Chemokinesignaling pathway; Cytokine-cytokine receptor interaction; CytosolicDNA-sensing pathway; IL12-mediated signaling events; Salmonella infection
• Function: chemokine activity