Recombinant Human PEST Proteolytic Signal Containing Nuclear Protein, His-tagged

• Cat.No.: PCNP-5092H
• Product Overview: Recombinant humanPCNP protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: PCNP (PESTproteolytic signal containing nuclear protein) is a nuclear protein impliedto play a role in cell cycle regulation and tumorigenesis. This protein isubiquitinated post-translationally by NIRF, an ubiquitin ligase. PCNP exsistsas three isoforms produced by alternative splicing events and may be involvedin cell cycle regulation.
• Concentration: 1 mg/ml
• Form: Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, with 10% glycerol and 1 mM DTT.
• Purity: > 95% pure bySDS-PAGE
• Sequence: 1-178 amino acids:MGSSHHHHHH SSGLVPRGSH MGSHMADGKA GDEKPEKSQR AGAAGGPEEE AEKPVKTKTV SSSNGGESSSRSAEKRSAEE EAADLPTKPT KISKFGFAIG SQTTKKASAI SIKLGSSKPK ETVPTLAPKT LSVAAAFNEDEDSEPEEMPP EAKMRMKNIG RDTPTSAGPN SFNKGKHGFS DNQKLWERNI KSHLGNVHDQ DN
• Molecular Mass: 21.5 kDa
• Applications: SDS-PAGE
• Storage: Store at 4 deg C forshort term storage. Aliquot and store at -20 deg C or -70 deg C for long termstorage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: PCNP

Gene Information

• Gene Name: PCNP PEST proteolytic signalcontaining nuclear protein [ Homo sapiens ]
• Synonyms: PCNP; PESTproteolytic signal containing nuclear protein; DKFZp781I24156; PESTproteolytic signal-containing nuclear protein; OTTHUMP00000214092;PEST-containing nuclear protein
• Gene ID: 57092
• mRNA Refseq: NM_020357
• Protein Refseq: NP_065090
• UniProt ID: Q8WW12
• Chromosome Location: 3q12.3
• Function: protein binding