Recombinant Human SSU72 RNA Polymerase II CTD Phosphatase Homolog (S. cerevisiae), His-tagged SSU72-1401H

Recombinant Human SSU72 RNA Polymerase II CTD Phosphatase Homolog (S. cerevisiae), His-tagged

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Recombinant Human SSU72 RNA Polymerase II CTD Phosphatase Homolog (S. cerevisiae), His-tagged

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Cat. No. : SSU72-1401H
Product Overview : Recombinanthuman SSU72protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventionalchromatography techniques.
Description : SSU72 is a highlyconserved homologue of yeast Ssu72, a CTD phosphatase and a component of thepolyadenylation/ termination machinery. Existing as multiple alternativelyspliced isoforms, SSU72 interacts with TFIIB, Rb and DNAM-1 and functions tocatalyze the dephosphorylation of target proteins, possibly playing a role inRNA processing and termination via dephosphorylation of Pol II.
Form : Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl.
Molecular Weight : 25 kDa (217aa),confirmed by MALDI-TOF.
Purity : > 95%by SDS-PAGE
Concentration : 1 mg/ml(determined by Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSMPSSPLR VAVVCSSNQN RSMEAHNILS KRGFSVRSFG TGTHVKLPGPAPDKPNVYDF KTTYDQMYND LLRKDKELYT QNGILHMLDR NKRIKPRPERFQNCKDLFDL ILTCEERVYD QVVEDLNSRE QETCQPVHVV NVDIQDNHEE ATLGAFLICE LCQCIQHTEDMENEIDELLQ EFEEKSGRTF LHTVCFY
Storage : Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
nullValue_other :
Functionhydrolaseactivity; phosphoproteinphosphatase activity
Gene Name : SSU72SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) [ Homosapiens ]
Official Symbol : SSU72
Synonyms : SSU72; SSU72 RNA polymerase II CTD phosphatase homolog(S. cerevisiae); HSPC182; FLJ13048; PNAS-120; RNA polymerase II subunit A C-terminal domainphosphatase SSU72; CTD phosphatase SSU72; OTTHUMP00000000597; EC3.1.3.16; Ssu72 RNA polymerase IICTD phosphatase homolog (yeast); OTTHUMP00000000598; OTTHUMP00000000599;OTTHUMP00000039178
Gene ID : 29101
mRNA Refseq : NM_014188
Protein Refseq : NP_054907
UniProt ID : Q9NP77
Chromosome Location : 1p36.3

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