Recombinant Rat Growth Hormone 1

• Cat.No.: Gh1-372R
• Product Overview: Recombinant Rat Gh1 produced in E. coli is a single,non-glycosylated, polypeptide chain containing 190 amino acids and having aMW 21.81 kDa.

Specification

• Cat. No.: Gh1-372R
• Description: A polypeptide that is secreted by the adenohypophysis. Gh1, alsoknown as somatotropin, stimulates mitosis, cell differentiation and cellgrowth. Species-specific Gh1 have been synthesized.GH1 augments the cytolyticactivity of T-cells, antibody synthesis, and granulocyte differentiationinduced by GM-CSF. GH1 also enhances production of TNF-alpha, generation ofsuperoxide anions from peritoneal macrophages, and natural killer activity.
• Source: E. coli
• Form: Rat Gh1(1 mg/ml) was lyophilized after extensive dialyses against 5 mM phosphate buffer+ 5 mg mannitol + 1 mg glycine.
• Purity: Greater than 97.0%as determined by analysis by RP-HPLC and by analysis by SDSPAGE.
• Reconstitution: It is recommended to reconstitute thelyophilized Gh1 Rat in sterile 18MΩ-cm H2O not less than 100 ug/ml,which can then be further diluted to other aqueous solutions.
• Amino Acid Sequence: The sequence of thefirst five N-terminal amino acids is Met-Phe-Pro-Thr-Ile.
• Storage: Lyophilized Growth Hormone Ratalthough stable at room temperature for 3 weeks, should be stored desiccatedbelow -20°C. Upon reconstitution Gh1 Rat should be stored at 2-4°C between2-7 days and for future use below -20°C. For long term storage it is recommendedto add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
• OfficialSymbol: Gh1

Gene Information

• Gene Name: Gh1growth hormone 1 [ Rattus norvegicus ]
• Synonyms: Gh1; growthhormone 1; Gh; RNGHGP; somatotropin
• Gene ID: 24391
• mRNA Refseq: NM_001034848
• Protein Refseq: NP_001030020
• UniProt ID: P01244
• Chromosome Location: 10q32
• Pathway: Adipogenesis; Diabetes pathways; Jak-STATsignaling pathway; Neuroactive ligand-receptor interaction; Synthesis,Secretion, and Deacylation of Ghrelin
• Function: growthfactor activity; growth hormone receptor binding; hormone activity; metal ionbinding; prolactin receptor binding