"CSNK2A1" Related Products


Recombinant Human Casein Kinase 2, Alpha 1 Polypeptide, His-tagged

Cat. No. : CSNK2A1-1208H
Product Overview : Recombinant humanfull length CSNK2A1 with His tag. No special measures were taken to activatethis kinase.
Description : Casein kinase IIsubunit alpha is an enzyme that in humans is encoded by the CSNK2A1 gene.Casein kinase II is a serine/threonine protein kinase that phosphorylatesacidic proteins such as casein. The kinase exists as a tetramer and iscomposed of an alpha, an alpha-prime, and two beta subunits. The alphasubunits contain the catalytic activity while the beta subunits undergoautophosphorylation. The protein encoded by this gene represents the alphasubunit. While this gene is found on chromosome 20, a related transcribedpseudogene is found on chromosome 11. Three transcript variants encoding twodifferent proteins have been found for this gene.
Source : Insect cells
Species : Human
Form : Liquid in 50 mMTris, pH 7.5 + 100 mM NaCl + 0.05 mM EDTA + 0.05% Triton X-100 + 2 mM DTT +50% glycerol.
Molecular Weight : 47.9 kDa
Concentration : 0.37 mg/ml
Purity : ≥ 90% as determined by SDS-PAGE analysis.
Storage : Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : CSNK2A1
PDB rendering basedon 1jwh. :

Gene Name : CSNK2A1 casein kinase 2, alpha 1polypeptide [ Homo sapiens ]
Synonyms : CSNK2A1; caseinkinase 2, alpha 1 polypeptide; CKII; CK2A1; casein kinase II subunit alpha;CK II alpha; OTTHUMP00000029925; OTTHUMP00000029926; protein kinase CK2; CK2catalytic subunit alpha; casein kinase II alpha 1 subunit; EC 2.7.11
Gene ID : 1457
mRNA Refseq : NM_001895
Protein Refseq : NP_001886
MIM : 115440
UniProt ID : P68400
Chromosome Location : 20p13
Pathway : Adherens junction;Alpha-synuclein signaling; Axon guidance; BCR signaling pathway;Developmental Biology; Herpes simplex infection; L1CAM interactions; Measles;PDGFR-alpha signaling pathway; Presenilin action in Notch and Wnt signaling;Ribosome biogenesis in eukaryotes; Signal transduction by L1; Tight junction;Wnt Signaling Pathway NetPath; Wnt signaling pathway
Function : ATP binding;beta-catenin binding; nucleotide binding; protein N-terminus binding; proteinbinding; protein phosphatase regulator activity; protein serine/threoninekinase activity; transferase activity, transferring phosphorus-containinggroups

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