"DAPK2" Related Products

Recombinant Human Death-Associated Protein Kinase 2, His-tagged

Cat. No. : DAPK2-675H
Product Overview : Recombinant humanfull length DAPK2 with His tag. No special measures were taken to activatethis kinase.
Description : Death-associatedprotein kinase 2 is an enzyme that in humans is encoded by the DAPK2 gene.This gene encodes a protein that belongs to the serine/threonine proteinkinase family. This protein contains a N-terminal protein kinase domainfollowed by a conserved calmodulin-binding domain with significant similarityto that of death-associated protein kinase 1 (DAPK1), a positive regulator ofprogrammed cell death. Overexpression of this gene was shown to induce cellapoptosis. It uses multiple polyadenylation sites. The DAPK2 mRNA may undergoalternative splicing to produce a DAPK3-like encoding transcript.
Source : Insect cells
Species : Human
Form : Liquid in 50 mMTris, pH 7.5 + 300 mM NaCl + 0.5 mM EDTA + 0.05% Brij-35 + 2 Mm DTT + 50%glycerol.
Molecular Weight : 47.9 kDa
Concentration : 0.28 mg/ml
Purity : ≥ 90% as determinedby SDS-PAGE analysis.
Storage : Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : DAPK2
Gene Name : DAPK2 death-associated proteinkinase 2 [ Homo sapiens ]
Synonyms : DAPK2;death-associated protein kinase 2; DRP1; DRP-1; MGC119312; death-associatedprotein kinase 2; DAP kinase 2; OTTHUMP00000163874; DAP-kinase-related protein1 beta isoform; DAP-kinase-related protein 1; EC 2.7.11.1; EC 2.7.11
Gene ID : 23604
mRNA Refseq : NM_014326
Protein Refseq : NP_055141
UniProt ID : Q9UIK4
Chromosome Location : 15q22.31
Pathway : Apoptosis; Bladdercancer; Pathways in cancer; Regulation of Apoptosis; Role of DCC inregulating apoptosis
Function : ATP binding;calmodulin binding; calmodulin-dependent protein kinase activity; identicalprotein binding; nucleotide binding; protein serine/threonine kinase activity

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