Recombinant Human Death-Associated Protein Kinase 2, His-tagged
Cat.No. : |
DAPK2-675H |
Product Overview : |
Recombinant humanfull length DAPK2 with His tag. No special measures were taken to activatethis kinase. |
- Specification
- Gene Information
- Related Products
Cat. No. : |
DAPK2-675H |
Description : |
Death-associatedprotein kinase 2 is an enzyme that in humans is encoded by the DAPK2 gene.This gene encodes a protein that belongs to the serine/threonine proteinkinase family. This protein contains a N-terminal protein kinase domainfollowed by a conserved calmodulin-binding domain with significant similarityto that of death-associated protein kinase 1 (DAPK1), a positive regulator ofprogrammed cell death. Overexpression of this gene was shown to induce cellapoptosis. It uses multiple polyadenylation sites. The DAPK2 mRNA may undergoalternative splicing to produce a DAPK3-like encoding transcript. |
Source : |
Insect cells |
Species : |
Human |
Form : |
Liquid in 50 mMTris, pH 7.5 + 300 mM NaCl + 0.5 mM EDTA + 0.05% Brij-35 + 2 Mm DTT + 50%glycerol. |
Molecular Weight : |
47.9 kDa |
Concentration : |
0.28 mg/ml |
Purity : |
≥ 90% as determinedby SDS-PAGE analysis. |
Storage : |
Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : |
DAPK2 |
Gene Name : |
DAPK2 death-associated proteinkinase 2 [ Homo sapiens ] |
Synonyms : |
DAPK2;death-associated protein kinase 2; DRP1; DRP-1; MGC119312; death-associatedprotein kinase 2; DAP kinase 2; OTTHUMP00000163874; DAP-kinase-related protein1 beta isoform; DAP-kinase-related protein 1; EC 2.7.11.1; EC 2.7.11 |
Gene ID : |
23604 |
mRNA Refseq : |
NM_014326 |
Protein Refseq : |
NP_055141 |
UniProt ID : |
Q9UIK4 |
Chromosome Location : |
15q22.31 |
Pathway : |
Apoptosis; Bladdercancer; Pathways in cancer; Regulation of Apoptosis; Role of DCC inregulating apoptosis |
Function : |
ATP binding;calmodulin binding; calmodulin-dependent protein kinase activity; identicalprotein binding; nucleotide binding; protein serine/threonine kinase activity |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.