Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase I CAMK1-47H

Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase I

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Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase I

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Cat. No. : CAMK1-47H
Product Overview : Recombinant fulllength human CAMK1.
Description : CAMK1 is an enzyme that in humans is encoded bythe CAMK1 gene. CAMK1 is expressed in many tissues and is acomponent of a calmodulin-dependent protein kinase cascade.Calcium/calmodulin directly activates CAMK1by binding to the enzyme and indirectly promotes the phosphorylation andsynergistic activation of the enzyme by CAMK1.
Source : E. coli
Species : Human
Form : Sterile filteredliquid in 20 mM HEPES-KOH, pH 7.0 + 50 mM NaCl + 1 mM EDTA + 1 mM DTT.
Concentration : 1 mg/ml
Purity : > 90% asdetermined by SDS-PAGE analysis.
Endotoxin Level : < 0.1 ng/µg ofCALM1
Biological Activity : Assayed for calciumbinding and activation of MLCK.
Applications : ELISA; InhibitionAssays; Western Blot; The optimal concentration should be determined by theuser for each specific application.
Storage : Stable for 1 year inworking aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : CAMK1
Gene Name : CAMK1calcium/calmodulin-dependent protein kinase I [ Homo sapiens ]
Synonyms : CAMK1;calcium/calmodulin-dependent protein kinase I; CAMKI; CaMKI; MGC120317;MGC120318; calcium/calmodulin-dependent protein kinase type 1; caM-KI;CaM-KI; caMKI-alpha; CaMKI-alpha; CaM kinase I; OTTHUMP00000158527; caMkinase I alpha; EC 2.7.11.17
Gene ID : 8536
mRNA Refseq : NM_003656
Protein Refseq : NP_003647
MIM : 604998
UniProt ID : Q14012
Chromosome Location : 3p25.3
Pathway : Calcium Regulationin the Cardiac Cell
Function : ATP binding;calmodulin binding; calmodulin-dependent protein kinase activity; nucleotidebinding; protein binding

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