Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase I

• Cat.No.: CAMK1-47H
• Product Overview: Recombinant fulllength human CAMK1.

Specification

• Cat. No.: CAMK1-47H
• Description: CAMK1 is an enzyme that in humans is encoded bythe CAMK1 gene. CAMK1 is expressed in many tissues and is acomponent of a calmodulin-dependent protein kinase cascade.Calcium/calmodulin directly activates CAMK1by binding to the enzyme and indirectly promotes the phosphorylation andsynergistic activation of the enzyme by CAMK1.
• Source: E. coli
• Species: Human
• Form: Sterile filteredliquid in 20 mM HEPES-KOH, pH 7.0 + 50 mM NaCl + 1 mM EDTA + 1 mM DTT.
• Concentration: 1 mg/ml
• Purity: > 90% asdetermined by SDS-PAGE analysis.
• Endotoxin Level: < 0.1 ng/µg ofCALM1
• Biological Activity: Assayed for calciumbinding and activation of MLCK.
• Applications: ELISA; InhibitionAssays; Western Blot; The optimal concentration should be determined by theuser for each specific application.
• Storage: Stable for 1 year inworking aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: CAMK1

Gene Information

• Gene Name: CAMK1calcium/calmodulin-dependent protein kinase I [ Homo sapiens ]
• Synonyms: CAMK1;calcium/calmodulin-dependent protein kinase I; CAMKI; CaMKI; MGC120317;MGC120318; calcium/calmodulin-dependent protein kinase type 1; caM-KI;CaM-KI; caMKI-alpha; CaMKI-alpha; CaM kinase I; OTTHUMP00000158527; caMkinase I alpha; EC 2.7.11.17
• Gene ID: 8536
• mRNA Refseq: NM_003656
• Protein Refseq: NP_003647
• MIM: 604998
• UniProt ID: Q14012
• Chromosome Location: 3p25.3
• Pathway: Calcium Regulationin the Cardiac Cell
• Function: ATP binding;calmodulin binding; calmodulin-dependent protein kinase activity; nucleotidebinding; protein binding