Recombinant Human Protein Kinase N1, GST-tagged

• Cat.No.: PKN1-1289H
• Product Overview: Recombinant humanfull length PKN1, GST-tagged.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Description: PKN1 belongs to theprotein kinase C superfamily. This kinase is activated by the Rho family ofsmall G proteins and may mediate the Rho-dependent signaling pathway. This kinasecan also be activated by phospholipids. No special measures were taken toactivate this kinase.
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol
• Molecular Weight: 132.1 kDa
• Storage: Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: PKN1
• Full Length: Full L.

Gene Information

• Gene Name: PKN1 protein kinase N1 [ Homosapiens ]
• Synonyms: PKN1; protein kinaseN1; DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; MGC46204; PKN-ALPHA;serine/threonine-protein kinase N1; OTTHUMP00000037582; OTTHUMP00000037583;protein kinase C-like 1; protein kinase PKN-alpha; protein kinase C-like PKN;serine-threonine kinase N; protease-activated kinase 1; protein kinaseC-related kinase 1; protein-kinase C-related kinase 1; serine-threonineprotein kinase N; serine/threonine protein kinase N; EC 2.7.11.13
• Gene ID: 5585
• mRNA Refseq: NM_213560
• Protein Refseq: NP_998725
• MIM: 601032
• UniProt ID: Q16512
• Chromosome Location: 19p13.12
• Pathway: G13 SignalingPathway; Regulation of Androgen receptor activity; RhoA signaling pathway;Salmonella infection; Signaling mediated by p38-gamma and p38-delta;TNF-alpha/NF-kB Signaling Pathway
• Function: ATP binding; GTP-Rhobinding; Rac GTPase binding; androgen receptor binding; chromatin binding;histone binding; histone deacetylase binding; histone kinase activity (H3-T11specific); ligand-dependent nuclear receptor transcription coactivatoractivity; nucleotide binding; protein binding; protein kinase C activity;protein kinase C binding; protein kinase activity; protein serine/threoninekinase activity