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Recombinant Human Protein Kinase N1, GST-tagged

Cat. No.: PKN1-1289H
Product Overview: Recombinant humanfull length PKN1, GST-tagged.
Description: PKN1 belongs to theprotein kinase C superfamily. This kinase is activated by the Rho family ofsmall G proteins and may mediate the Rho-dependent signaling pathway. This kinasecan also be activated by phospholipids. No special measures were taken toactivate this kinase.
Source: Insect cells
Species: Human
Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol
Molecular Weight: 132.1 kDa
Storage: Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol: PKN1
Gene Name: PKN1 protein kinase N1 [ Homosapiens ]
Synonyms: PKN1; protein kinaseN1; DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; MGC46204; PKN-ALPHA;serine/threonine-protein kinase N1; OTTHUMP00000037582; OTTHUMP00000037583;protein kinase C-like 1; protein kinase PKN-alpha; protein kinase C-like PKN;serine-threonine kinase N; protease-activated kinase 1; protein kinaseC-related kinase 1; protein-kinase C-related kinase 1; serine-threonineprotein kinase N; serine/threonine protein kinase N; EC 2.7.11.13
Gene ID: 5585
mRNA Refseq: NM_213560
Protein Refseq: NP_998725
MIM: 601032
UniProt ID: Q16512
Chromosome Location: 19p13.12
Pathway: G13 SignalingPathway; Regulation of Androgen receptor activity; RhoA signaling pathway;Salmonella infection; Signaling mediated by p38-gamma and p38-delta;TNF-alpha/NF-kB Signaling Pathway
Function: ATP binding; GTP-Rhobinding; Rac GTPase binding; androgen receptor binding; chromatin binding;histone binding; histone deacetylase binding; histone kinase activity (H3-T11specific); ligand-dependent nuclear receptor transcription coactivatoractivity; nucleotide binding; protein binding; protein kinase C activity;protein kinase C binding; protein kinase activity; protein serine/threoninekinase activity

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