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Recombinant Human Aldolase C, Fructose-Bisphosphate, His-tagged

Cat. No.: ALDOC-969H
Product Overview: ALDOC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques(1-364 aa).
Description: ALDOC, also known as aldolase C, is a member of the class I fructose-biphosphatealdolase family. This protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively. It is expressed specifically in the hippocampus and Purkinje cells of the brain.
Form: Liquid. In 20mM Tris-HClbuffer(pH 8.0) containing 10% glycerol,2mM DTT, 0.1M NaCl.
Molecular Weight: 41.6 kDa (384aa), confirmed by MALDI-TOF
Purity: > 95 % by SDS - PAGE
Concentration: 1 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYR QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF SYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Gene Name: ALDOC aldolase C, fructose-bisphosphate [Homo sapiens]
Synonyms: ALDOC; OTTHUMP00000163437;ALDC; fructoaldolase C;aldolaseC,fructose-bisphosphate; Brain-type aldolase; fructose-bisphosphatealdolase C; aldolase 3; EC 4.1.2.13; fructose-1,6-biphosphate triosephosphatelyase
Gene ID: 230
mRNA Refseq: NM_005165
Protein Refseq: NP_005156
MIM: 103870
UniProt ID: P09972
Chromosome Location: 17cen-q12
Function: cytoskeletal protein binding; fructose-bisphosphatealdolase activity; lyase activity; protein binding

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