Active Recombinant Human PIN4 protein, His-tagged
Cat.No. : | PIN4-974H |
Product Overview : | Recombinant Human PIN4(1-156aa) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | PIN4, also known as Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, is peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and is essential for cell cycle regulation. There are two different isoforms which are PAR14 and PAR17. PIN4/PAR17 was imported into mitochondria in a time and membrane potential-dependent manner, where it reached the mitochondrial matrix. Moreover, Pin4 protein was shown to bind to double-stranded DNA under physiological salt conditions. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 0.1mM PMSF |
Bio-activity : | Specific activity is >300 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin. |
Molecular Mass : | 18.8 kDa (176aa), confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSHEKHGKIMEAM EKLKSGMRFN EVAAQYSEDK ARQGGDLGWM TRGSMVGPFQ EAAFALPVSG MDKPVFTDPP VKTKFGYHII MVEGRKMPMAGLLKGL VRQLERFSVQ QQASKMPPKG KSGSGKAGKG GAASGSDSAD KKAQGPKGGG NAVKVRHIL |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | PIN4 protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) [ Homo sapiens ] |
Official Symbol : | PIN4 |
Synonyms : | PIN4; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin); protein (peptidyl prolyl cis/trans isomerase) NIMA interacting, 4 (parvulin); peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; EPVH; PAR14; PAR17; hEPVH; hPar14; hPar17; PPIase PIN4; parvulin-14; parvulin-17; rotamase PIN4; eukaryotic parvulin homolog; peptidyl-prolyl cis-trans isomerase Pin4; peptidyl-prolyl cis/trans isomerase EPVH; MGC138486; |
Gene ID : | 5303 |
mRNA Refseq : | NM_001170747 |
Protein Refseq : | NP_001164218 |
MIM : | 300252 |
UniProt ID : | Q9Y237 |
Chromosome Location : | Xq13.1 |
Function : | DNA binding; bent DNA binding; double-stranded DNA binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; |
Products Types
◆ Recombinant Protein | ||
PIN4-6748M | Recombinant Mouse PIN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIN4-4910H | Recombinant Human PIN4 Protein (Ser23-Arg130), N-His tagged | +Inquiry |
PIN4-30962TH | Recombinant Human PIN4, His-tagged | +Inquiry |
PIN4-12819M | Recombinant Mouse PIN4 Protein | +Inquiry |
PIN4-2741Z | Recombinant Zebrafish PIN4 | +Inquiry |
◆ Lysates | ||
PIN4-3178HCL | Recombinant Human PIN4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket