"TPSG1" Related Products

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Recombinant Human Tryptase Gamma 1, His-tagged

Cat. No.: TPSG1-510H
Product Overview: Recombinant Human TPSG1protein was expressed in Murine myeloma cell line with a C-terminal 10-Histag. Arg20-Arg281.
Description: Human TPSG1 issynthesized as a 321 amino acid preproenzyme with a C-terminal transmembraneanchor. The proenzyme can be cleaved by trypsin to form the active enzyme. Asmediators of inflammatory and allergic response, mast cells are foundthroughout the body concentrated near blood vessels in connective tissue andthe mucous membranes of the respiratory and gastrointestinal tract.
Source: Murine myeloma cellline, NS0-derived.
Form: Supplied as a 0.2 μmfiltered solution in Tris, CaCl2, NaCl, Brij-35 and Glycerol.
N-terminalSequence: Arg20
Molecular Weight: 29 kDa
Activity: Measuredby its ability to cleave the fluorogenic peptide substrate,Mca-RPKPVE-Nval-WRK (Dnp)-NH2, The specific activity is > 70pmoles/min/μg, as measured under the described conditions.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE: 36 kDa,reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months fromdate of receipt, -70°C as supplied. 3 months, -70°C under sterile conditionsafter opening.
Gene Name: TPSG1 tryptase gamma 1 [ Homosapiens ]
Official Symbol: TPSG1
Synonyms: TPSG1; tryptasegamma 1; TMT; trpA; PRSS31; tryptase gamma; gamma I; gamma II; lung tryptase;skin tryptase; tryptase gamma I; tryptase gamma II; mast cell tryptase;pituitary tryptase; serine protease 31; mast cell protease II; transmembranetryptase;EC 3.4.21.59; EC=3.4.21.-; OTTHUMP00000115529
Gene ID: 25823
mRNA Refseq: NM_012467
Protein Refseq: NP_036599
MIM: 609341
UniProt ID: Q9NRR2
Chromosome Location: 16p13.3
Function: peptidase activity; serine-typeendopeptidase activity; serine-type peptidase activity

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