"AGGF1" Related Products

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Recombinant Human Angiogenic Factor With G Patch And FHA Domains 1, His-tagged

Cat. No.: AGGF1-543H
Product Overview: Recombinant Human AGGF1protein was expressed in Murine myeloma cell line with a N-terminal 9-His tag.Ala2-Glu714.
Description: AGGF1, wasidentified by its association with KlippelTrenaunay syndrome (KTS), acongenital vascular morphogenesis disorder. Two genetic alterations found inKTS lead to aberrant expression or function of AGGF1: a chromosomal translocationthat falls within the AGGF1 promoter and a glutamate to lysine point mutationat position 133. The human AGGF1 cDNA encodes a 714 amino acid (aa) precursorwith a coiled coil domain, an FHA domain, a G-patch domain, and an OCREdomain. FHA domains bind phosphorylated threonine and tyrosine residues.
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence: His
Molecular Weight: 82.0 kDa
Activity: Measured by itsbinding ability in a functional ELISA. Immobilized rh AGGF1 at 1 μg/mL (100μL/well) can bind rhTWEAK with a linear range of 0.8-50 ng/mL.
Endotoxin Level: < 1.0EU per 1 μg of the protein by the LAL method.
SDS-PAGE: 120-140 kDa,reducing conditions.
Purity: > 95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: 100μg/mL in sterile PBS.
Storage: Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditionsafter reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name: AGGF1 angiogenic factor with Gpatch and FHA domains 1 [ Homo sapiens ]
Official Symbol: AGGF1
Synonyms: AGGF1; angiogenicfactor with G patch and FHA domains 1; VG5Q; GPATC7;GPATCH7; HSU84971; HUS84971; angiogenic factor VG5Q; vasculogenesis gene on5q protein; patch domain-containing protein 7; G5Q
Gene ID: 55109
mRNA Refseq: NM_018046
Protein Refseq: NP_060516
MIM: 608464
UniProt ID: Q8N302
Chromosome Location: 5q13.3
Function: eukaryotic cellsurface binding; nucleic acid binding; protein binding

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