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Recombinant Human Abhydrolase Domain Containing 10, His-tagged

Cat.No. : ABHD10-2400H
Product Overview : Recombinant humanABHD10 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography.
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Cat. No. : ABHD10-2400H
Description : ABHD10, also knownas abhydrolase domain-containing protein 10, belongs to the AB hydrolasesuperfamily.
Form : 20mM Tris-HCl buffer(pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Molecular Weight : 30.9 kDa (279aa),confirmed by MALDI-TOF
Purity : > 90% by SDS -PAGE
Concentration : 1 mg/ml (determinedby Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMTSLSF LNRPDLPNLA YKKLKGKSPG IIFIPGYLSY MNGTKALAIE EFCKSLGHACIRFDYSGVGS SDGNSEESTL GKWRKDVLSI IDDLADGPQI LVGSSLGGWL MLHAAIARPE KVVALIGVATAADTLVTKFN QLPVELKKEV EMKGVWSMPS KYSEEGVYNV QYSFIKEAEH HCLLHSPIPV NCPIRLLHGMKDDIVPWHTS MQVADRVLST DVDVILRKHS DHRMREKADI QLLVYTIDDL IDKLSTIVN
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : ABHD10 abhydrolase domaincontaining 10 [ Homo sapiens ]
Official Symbol : ABHD10
Synonyms : ABHD10;abhydrolase domain containing 10; Abhydrolase domain-containing protein 10,mitochondrial; FLJ11342; OTTHUMP00000214651; OTTHUMP00000214654; EC 3.4.-.
Gene ID : 55347
mRNA Refseq : NM_018394
Protein Refseq : NP_060864
UniProt ID : Q9NUJ1
Chromosome Location : 3q13.2
Function : peptidase activity; serine-type peptidaseactivity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What kind of chemical compounds can interact with the ABHD10 protein? 03/11/2021

 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid.

Brefily introduce a protein function of the ABHD10? 11/06/2019

It regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability

How is the function of the ABDH10 when it act as a prognostic marker? 10/04/2019

Prognostic marker in renal cancer (favorable) and cervical cancer (favorable).

Does the ABHD 10 protein can be detect in blood by proximity extension assay? 05/10/2019

No

Please list at least three cellular compnents of the ABHD10? 04/01/2018

Cell projection, cytoskeleton, and non-membrane-bounded organelle.

What is the name of ABHD10 inhibitor, which have function of increase the catalytic effciency of AcMPAG (mycophenolic acid acyl glucuronide) formation in human liver homogenate? 01/14/2017

Phenylmethyl-sulfonyl fluride (PMSF).

What is the representative subtrate drug of ABHD10? 01/09/2017

Mycophenolic acid acyl-glucurnide.

What is the proportion of amino acid homology does ABHD10 have between humans and rodents (mice and rats)? 10/21/2016

Approximately 75%.

What biological process does ABHD10 regulate in human liver? 09/16/2016

ABHD10 modulates Probenecid Acyl Glucuronidation in human liver.

ABHD10 plays a key role in the metabolism of the immunosuppressant mycophenolate mofetil (MMF), because it led to the deglucuronidation in human liver of acyl glucuronide metabolite (AcMPAG). What might this information suggest about the ABHD10 protein? 06/07/2016

ABHD10 exerted a detoxifying effect.

Customer Reviews (4)

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Reviews
08/28/2019

    Suitable price, great!

    03/27/2018

      Fast shipping and good product.

      12/10/2017

        Nice performance in electrophoresis.

        07/12/2017

          Good work in purification process!

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