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Recombinant Human Clathrin, Light Chain A, His-tagged

Cat.No. : CLTA-6787H
Product Overview : Recombinant humanCLTA protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques
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  • Gene Information
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Cat. No. : CLTA-6787H
Description : Clathrin, lightchain A, also known as CLTA, belongs to the clathrin family. Clathrin is alarge, soluble protein composed of heavy and light chains. It is a majorcytosolic coat protein in pits and vesicles originating from the plasmamembrane and the trans-Golgi network. In receptor-mediated endocytosis,receptor proteins are captured by Clathrin-coated vesicles. CLTA is one oftwo clathrin light chain proteins which are believed to function asregulatory elements
Form : Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Molecular Weight : 26.2 kDa (242aa),confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Purity : > 90% by SDS -PAGE
Concentration : 1 mg/ml (determinedby Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMAELDP FGAPAGAPGG PALGNGVAGA GEEDPAAAFL AQQESEIAGI ENDEAFAILDGGAPGPQPHGEPPGGPDAVDGVMNGEYYQE SNGPTDSYAA ISQVDRLQSE PESIRKWREE QMERLEALDA NSRKQEAEWK EKAIKELEEWYARQDEQLQKTKANNRAAEEAFVNDIDESS PGTEWERVAR LCDFNPKSSK QAKDVSRMRS VLISLKQAPL VH
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles
Officialsymbol : CLTA
Gene Name : CLTA clathrin, light chain A[Homo sapiens]
Synonyms : clathrin,light chain A; OTTHUMP00000215626; clathrin, light polypeptide (Lca);OTTHUMP00000215628; Lca; clathrin light chain A; OTTHUMP00000021365;OTTHUMP00000021366; OTTHUMP00000215627
Gene ID : 1211
mRNA Refseq : NM_001833
Protein Refseq : NP_001824
MIM : 118960
UniProt ID : P09496
Chromosome Location : 9p13
Pathway : Arf1pathway, organism-specific biosystem; Axon guidance, organism-specificbiosystem; Bacterial invasion of epithelial cells, organism-specificbiosystem; Bacterial invasion of epithelial cells, conserved biosystem; C-MYBtranscription factor network, organism-specific biosystem; Clathrin derivedvesicle budding, organism-specific biosystem
Function : molecular_function;peptide binding; structural molecule activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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