Cat.No. :	BMP2-867H
Product Overview :	Recombinant human BMP2 protein was expressed in E. coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.
Description :	BMP2 is multi-functional growth factor that belongs to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration.
Source :	E. coli
Species :	Human
Tag :	His
Form :	Liquid. In 10 mM Sodium acetate (pH 3.5).
Molecular Mass :	13.0 kDa(115aa)
Protein length :	283-396aa
AA Sequence :	MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Purity :	>90% by SDS - PAGE
Applications :	SDS-PAGE
Storage :	Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration :	1 mg/ml (determined by Bradford assay)

Gene Name :	BMP2 bone morphogenetic protein 2 [ Homo sapiens ]
Official Symbol :	BMP2
Synonyms :	BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2;
Gene ID :	650
mRNA Refseq :	NM_001200
Protein Refseq :	NP_001191
MIM :	112261
UniProt ID :	P12643
Chromosome Location :	20p12
Pathway :	Adipogenesis, organism-specific biosystem; BMP Signalling Pathway, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Heart Development, organism-specific biosystem;
Function :	BMP receptor binding; SMAD binding; activin receptor activity, type II; cytokine activity; growth factor activity; phosphatase activator activity; protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerization activity; receptor binding; retinol dehydrogenase activity; transmembrane receptor protein serine/threonine kinase activity;

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