Cat.No.:	BMP2-867H
Product Overview:	Recombinant human BMP2 protein was expressed in E. coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.
Description:	BMP2 is multi-functional growth factor that belongs to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration.
Source:	E. coli
Species:	Human
Tag:	His
Form:	Liquid. In 10 mM Sodium acetate (pH 3.5).
Molecular Mass:	13.0 kDa(115aa)
Protein length:	283-396aa
AA Sequence:	MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Purity:	>90% by SDS - PAGE
Applications:	SDS-PAGE
Storage:	Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration:	1 mg/ml (determined by Bradford assay)

Gene Name:	BMP2 bone morphogenetic protein 2 [ Homo sapiens ]
Official Symbol:	BMP2
Synonyms:	BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2;
Gene ID:	650
mRNA Refseq:	NM_001200
Protein Refseq:	NP_001191
MIM:	112261
UniProt ID:	P12643
Chromosome Location:	20p12
Pathway:	Adipogenesis, organism-specific biosystem; BMP Signalling Pathway, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Heart Development, organism-specific biosystem;
Function:	BMP receptor binding; SMAD binding; activin receptor activity, type II; cytokine activity; growth factor activity; phosphatase activator activity; protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerization activity; receptor binding; retinol dehydrogenase activity; transmembrane receptor protein serine/threonine kinase activity;

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