Recombinant Human Charged Multivesicular Body Protein 5, His-tagged

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Recombinant Human Charged Multivesicular Body Protein 5, His-tagged

CHMP5 Related Products

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Cat.No. : CHMP5-7172H
Product Overview : Recombinant human CHMP5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 27 kDa.
Description : CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol.
Molecular Mass : 27 kDa (243aa) confirmed by MALDI-TOF
Protein length : 1-219aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSHMNRLFG KAKPKAPPPS LTDCIGTVDS RAESIDKKIS RLDAELVKYK DQIKKMREGP AKNMVKQKAL RVLKQKRMYE QQRDNLAQQS FNMEQANYTI QSLKDTKTTV DAMKLGVKEM KKAYKQVKID QIEDLQDQLE DMMEDANEIQ EALSRSYGTP ELDEDDLEAE LDALGDELLA DEDSSYLDEA ASAPAIPEGV PTDTKNKDGV LVDEFGLPQI PAS
Purity : >80% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : CHMP5 charged multivesicular body protein 5 [ Homo sapiens ]
Official Symbol : CHMP5
Synonyms : CHMP5; charged multivesicular body protein 5; C9orf83, chromatin modifying protein 5 , chromosome 9 open reading frame 83 , SNF7DC2; CGI 34; HSPC177; Vps60; hVps60; SNF7 domain containing 2; chromatin modifying protein 5; chromatin-modifying protein 5; SNF7 domain-containing protein 2; apoptosis-related protein PNAS-2; vacuolar protein sorting-associated protein 60; CGI-34; PNAS-2; C9orf83; SNF7DC2;
Gene ID : 51510
mRNA Refseq : NM_001195536
Protein Refseq : NP_001182465
MIM : 610900
UniProt ID : Q9NZZ3
Chromosome Location : 9p13.3
Pathway : ESCRT-III complex, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Endosomal Sorting Complex Required For Transport (ESCRT), organism-specific biosystem; Membrane Trafficking, organism-specific biosystem;
Function : protein binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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