Active Recombinant Human CAMKK1, GST-tagged
Cat.No. : | CAMKK1-1374H |
Product Overview : | Recombinant full-length human CAMKK1 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | CAMKK1 or CAMKKα is a Ca(2+)/calmodulin-dependent protein kinase that activatesCaM-kinases I and IV via phosphorylation of their Thr(177) and Thr(196) residues, respectively. Recent studies have shown that the activity of CAMKK1 is decreased upon phosphorylation by cAMP-dependent protein kinase (PKA) The CAMKKalpha has been identified in intact cells as AMPKKs, predicting a significant role for this kinase in regulating AMPK activity in vivo. It has been shown that 2-deoxyglucose- and ionomycin-stimulated AMPK activity is substantially reduced in HeLa cells transfected with small interfering RNAs specific for CAMKKα. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 10 nmol/min/mg |
Molecular Mass : | ~94 kDa |
Protein length : | Full length |
Purity : | >90% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha [ Homo sapiens ] |
Official Symbol : | CAMKK1 |
Synonyms : | CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase 1; CAMKKA; DKFZp761M0423; MGC34095; caMKK 1; caM-KK 1; caM-KK alpha; CAMKK alpha protein; caM-kinase kinase 1; caM-kinase IV kinase; caM-kinase kinase alpha; calcium/calmodulin-dependent protein kinase kinase alpha; |
Gene ID : | 84254 |
mRNA Refseq : | NM_032294 |
Protein Refseq : | NP_115670 |
MIM : | 611411 |
UniProt ID : | Q8N5S9 |
Chromosome Location : | 17p13.3 |
Pathway : | Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; CREB phosphorylation through the activation of CaMKK, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Receptor Binding And Downstream Transmission In ThePostsynaptic Cell, organism-specific biosystem; Post NMDA receptor activation events, organism-specific biosystem; |
Function : | ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
CAMKK1-0172H | Recombinant Human CAMKK1 Protein (M1-S505), His tagged | +Inquiry |
CAMKK1-0338H | Active Recombinant Human CAMKK1 Protein, GST-Tagged | +Inquiry |
Camkk1-1946M | Recombinant Mouse Camkk1 Protein, Myc/DDK-tagged | +Inquiry |
CAMKK1-415H | Recombinant Human CAMKK1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CAMKK1-0339H | Recombinant Human CAMKK1 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CAMKK1-7873HCL | Recombinant Human CAMKK1 293 Cell Lysate | +Inquiry |
CAMKK1-7874HCL | Recombinant Human CAMKK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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