| Cat.No. : |
CDK11B-1534H |
| Product Overview : |
Recombinant full-length human CDK11 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description : |
CDK11 is a member of the cyclin-dependent kinase 11 family which is known to be essential for eukaryotic cell cycle control and it is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. CDK11 is a negative regulator of normal cell cycle progression and Its expression is regulated during murine embryogenesis, and its activity is coordinately regulated with that of p34 (cdc2) during the cell cycle. CDK11 gene may harbor 1 or more tumor suppressor genes that affected by chromosome 1p36 modifications in neuroblastoma. CDK11 could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. |
| Source : |
Sf9 |
| Species : |
Human |
| Tag : |
GST |
| Form : |
Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Molecular Mass : |
92 kDa |
| Protein length : |
Full length |
| Purity : |
>90% |
| Applications : |
Kinase Assay, Western Blot |
| Storage : |
Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
| Concentration : |
0.1μg/μl |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.