Recombinant Human RAS, GST-tagged

• Cat.No.: RAB40C-7036H
• Product Overview: Recombinant full-length human RAS was expressed in E. coli cells using a N-terminal GST tag.

Specification

• Description: The RAS gene superfamily encodes a group of closely related 21,000 dalton (p21) proteins with special affinity for guanine nucleotides (GTP). RAS and several other cellular proteins with similar biochemical properties are collectively known as G-proteins and they play key roles in a wide variety of cellular activities, including cell growth, differentiation, secretion, and protein trafficking. There are three forms of RAS gene in cells termed H-RAS, N-RAS, and K-RAS. RAS proteins play a direct causal role in human cancer and in other diseases. Mutant H-RAS, N-RAS, and K-RAS occur in varying frequencies in different tumor types. Other members of the RAS superfamily may also contribute to cancer.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~47 kDa
• Protein length: Full length
• Purity: >95%
• Applications: Kinase Assay, Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.2μg/μl

Gene Information

• Gene Name: RAB40C RAB40C, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAB40C
• Synonyms: RAB40C; RAB40C, member RAS oncogene family; RAS like, family 8, member C , RASL8C; ras-related protein Rab-40C; RARL; RAR like; RAS-like GTPase; rar-like protein; RAR (RAS like GTPASE) like; RAS-like, family 8, member C; SOCS box-containing protein RAR3; ras-like protein family member 8C; RASL8C
• Gene ID: 57799
• mRNA Refseq: NM_001172663
• Protein Refseq: NP_001166134
• UniProt ID: Q96S21
• Chromosome Location: 16p13.3
• Function: GTP binding; nucleotide binding