Recombinant Human AIP, His-tagged

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Recombinant Human AIP, His-tagged

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Cat. No. : AIP-3595H
Product Overview : Recombinant human AIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-330 aa).
Description : Aryl hydrocarbon receptor (AHR) interacting protein, also known as AIP, may play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It is a Cellular negative regulator of the hepatitis B virus (HBV) X protein. Also, AIP is a ubiquitously expressed protein, binds to HSP 90 and AHR through a highly conserved carboxy-terminal tetraticopeptide repeat domain.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Molecular Weight : 39.8 kDa (350aa), confirmed by MALDI-TOF
Purity : > 90% by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : AIP aryl hydrocarbon receptor interacting protein [ Homo sapiens ]
Official Symbol : AIP
Synonyms : AIP; ARA9; XAP2; FKBP16; FKBP37; SMTPHN; aryl hydrocarbon receptor interacting protein; XAP-2; AH receptor-interacting protein; OTTHUMP00000236411; OTTHUMP00000236412; HBV-X associated protein; immunophilin homolog ARA9; HBV X-associated protein 2; aryl hydrocarbon receptor-interacting protein; aryl-hydrocarbon receptor interacting protein; aryl-hydrocarbon receptor-interacting protein; Aryl-hydrocarbon receptor-interacting protein; Immunophilin homolog ARA9
Gene ID : 9049
mRNA Refseq : NM_003977
Protein Refseq : NP_003968
MIM : 605555
UniProt ID : O00170
Chromosome Location : 11q13.3
Function : protein binding; signal transducer activity; transcription coactivator activity; transcription factor binding; unfolded protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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