Rat Anti-Lgals9 Monoclonal Antibody


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Rat Anti-Lgals9 Monoclonal Antibody

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Cat.No. : DMABT-H18389
Product Overview : Rat Anti-Lgals9 Monoclonal Antibody
Antigen Description : Galectin-9 is a mammalian lectin with a molecular weight of 40 kD that has two conserved carbohydrate recognition domains (CRDs) and forms homodimers. It recognizes N-acetyllactosamine (Galbeta1-4GlcNAc) and T-antigen (Galbeta1-3GalNAc); Tim-3 has been reported as its ligand. Galectin-9 is expressed by lymphocytes, dendritic cells, granulocytes, eosinophils, astrocytes, endothelial cells, fibroblasts and thymus epithelial cells. It may be retained intracellularly or be transported to the cell surface where it is cleaved, thereby generating a soluble form. Galectin-9 is involved in events such as cell aggregation, cell adhesion, chemotaxis and apoptosis. Importantly for the regulation of the immune response, Galectin-9 induces regulatory T cells and suppresses Th1 and Th17 responses.
Target : Lgals9
Immunogen : Full length recombinant mouse Galectin-9 (M-type)
Host : Rat
Isotype : IgG2a, kappa
species : Mouse
Conjugation : PE
Applications : Flow Cyt
Preparation : The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Usage recommendation : Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Concentration : 0.2 mg/ml
Storage : The antibody solution should be stored undiluted at 4 °C and protected from prolonged exposure to light.Do not freeze.
Size : 50 μg;200 μg
Gene Name : Lgals9 lectin, galactose binding, soluble 9 [ Mus musculus ]
Official Symbol : Lgals9
Synonyms : LGALS9; lectin, galactose binding, soluble 9; galectin-9; lectin, galactose binding, soluble 5; gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545;
Gene ID : 16859
mRNA Refseq : NM_001159301
Protein Refseq : NP_001152773
Function : galactoside binding; signal transducer activity; sugar binding;

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