Recombinant Human CGB, His-tagged

• Cat.No.: CGB-7586H
• Product Overview: Recombinant human CGB protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Antigen Description: CGB is a member of the glycoprotein hormone beta chain family and is the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 17.9 kDa (168aa)
• Protein length: 21-165aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQ
• Purity: >85% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: CGB chorionic gonadotropin, beta polypeptide [ Homo sapiens ]
• Official Symbol: CGB
• Synonyms: CGB; chorionic gonadotropin, beta polypeptide; choriogonadotropin subunit beta; CGB3; CG-beta; chorionic gonadotropin beta chain; chorionic gonadotrophin chain beta; chorionic gonadotropin beta subunit; chorionic gonadotropin beta 3 subunit; CGB5; CGB7; CGB8; hCGB
• Gene ID: 1082
• mRNA Refseq: NM_000737
• Protein Refseq: NP_000728
• MIM: 118860
• UniProt ID: P01233
• Chromosome Location: 19q13.3
• Pathway: Glycoprotein hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Peptide hormone biosynthesis, organism-specific biosystem
• Function: hormone activity