Recombinant Human ARPC3, His-tagged

• Cat.No.: ARPC3-7591H
• Product Overview: Recombinant human ARPC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: Actin-related protein 2/3 complex subunit 3, also known as ARPC3, is one of seven subunits of the human Arp2/3 protein complex. Localized to the cytoplasm and cytoskeleton, ARPC3 is thought to interact with p20-ARC and play an important role in the structural integrity of the protein complex.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
• Molecular Mass: 22.9 kDa (201aa) confirmed by MALDI-TOF
• Protein length: 1-178aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPAYHSS LMDPDTKLIG NMALLPIRSQ FKGPAPRETK DTDIVDEAIY YFKANVFFKN YEIKNEADRT LIYITLYISE CLKKLQKCNS KSQGEKEMYT LGITNFPIPG EPGFPLNAIY AKPANKQEDE VMRAYLQQLR QETGLRLCEK VFDPQNDKPS KWWTCFVKRQ FMNKSLSGPG Q
• Purity: >95% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa [ Homo sapiens ]
• Official Symbol: ARPC3
• Synonyms: ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa; actin related protein 2/3 complex, subunit 3 (21 kD); actin-related protein 2/3 complex subunit 3; ARC21; p21 Arc; arp2/3 complex 21 kDa subunit; ARP2/3 protein complex subunit p21; p21-Arc
• Gene ID: 10094
• mRNA Refseq: NM_005719
• Protein Refseq: NP_005710
• MIM: 604225
• UniProt ID: O15145
• Chromosome Location: 12q24
• Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; CDC42 signaling events, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem
• Function: actin binding; protein binding; structural constituent of cytoskeleton