"BHMT" Related Products

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Recombinant Human BHMT, His-tagged

Cat.No.: BHMT-1232H
Product Overview: Recombinant human BHMT, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
Source: E.coli
Species: Human
Tag: His
Form: Liquid. 20mM Tris pH7.5, 20% glycerol.
Molecular Mass: 49.2 kDa (443 aa), confirmed by MALDI-TOF.
AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMPP VGGKKAKKGI LERLNAGEIV IGDGGFVFAL EKRGYVKAGP WTPEAAVEHP EAVRQLHREF LRAGSNVMQT FTFYASEDKL ENRGNYVLEK ISGQEVNEAA CDIARQVADE GDALVAGGVS QTPSYLSCKS ETEVKKVFLQ QLEVFMKKNV DFLIAEYFEH VEEAVWAVET LIASGKPVAA TMCIGPEGDL HGVPPGECAV RLVKAGASII GVNCHFDPTI SLKTVKLMKE GLEAARLKAH LMSQPLAYHT PDCNKQGFID LPEFPFGLEP RVATRWDIQK YAREAYNLGV RYIGGCCGFE PYHIRAIAEE LAPERGFLPP ASEKHGSWGS GLDMHTKPWV RARARKEYWE NLRIASGRPY NPSMSKPDGW GVTKGTAELM QQKEATTEQQ LKELFEKQKF KSQ
Purity: > 95% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: BHMT betaine-homocysteine methyltransferase [ Homo sapiens ]
Official Symbol: BHMT
Synonyms: BHMT; BHMT1; HEL-S-61p; betaine-homocysteine methyltransferase; Betaine-homocysteine S-methyltransferase 1; EC 2.1.1.5; betaine homocysteine methyltransferase
Gene ID: 635
mRNA Refseq: NM_001713
Protein Refseq: NP_001704
MIM: 602888
UniProt ID: Q93088
Chromosome Location: 5q14.1
Pathway: Cysteine and methionine metabolism; Glycine, serine and threonine metabolism; Metabolism of amino acids and derivatives
Function: S-adenosylmethionine-homocysteine S-methyltransferase activity; betaine-homocysteine S-methyltransferase activity; protein complex binding

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