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Recombinant Human CRYGD, His-tagged

Cat.No. : CRYGD-3634H
Product Overview : Recombinant human CRYGD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-174aa).
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  • Gene Information
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Cat. No. : CRYGD-3634H
Description : CRYGD belongs to the beta/gamma-crystallin family. Crystallins are the dominant structural components of the vertebrate eye lens. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Gamma-crystallins have been involved in cataract formation. Defects in CRYGD are a cause of cataract autosomal dominant (ADC), cataract congenital non-nuclear polymorphic autosomal dominant (CCP), cataract congenital cerulean type 3 (CCA3) and cataract crystalline aculeiform (CACA).
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 10% glycerol, 200mM NaCl
Molecular Weight : 22.9kDa (194aa), confirmed by MALDI-TOF
Purity : > 95% by SDS - PAGE
Concentration : 1mg/ml (determined by BCA)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MGKITLYEDR GFQGRHYECS SDHPNLQPYL SRCNSARVDS GCWMLYEQPN YSGLQYFLRR GDYADHQQWM GLSDSVRSCR LIPHSGSHRI RLYEREDYRG QMIEFTEDCS CLQDRFRFNE IHSLNVLEGS WVLYELSNYR GRQYLLMPGD YRRYQDWGAT NARVGSLRRV IDFS
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Publication :
Development of Ion Mobility-Mass Spectrometry as a High-throughput Approach for Structural Genomics. (2014)
Gene Name : CRYGD crystallin, gamma D [ Homo sapiens ]
Official Symbol : CRYGD
Synonyms : CRYGD; CCP; CACA; CCA3; CRYG4; cry-g-D; crystallin, gamma D; gamma-crystallin D; OTTHUMP00000163871; gamma crystallin 4; gamma-D-crystallin; gamma-crystallin 4; cry-g-D
Gene ID : 1421
mRNA Refseq : NM_006891
Protein Refseq : NP_008822
MIM : 123690
UniProt ID : P07320
Chromosome Location : 2q33-q35
Function : protein binding; structural constituent of eye lens

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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