Recombinant Human ARL6, His-tagged

• Cat.No.: ARL6-3544H
• Product Overview: Recombinant human ARL6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Cat. No.: ARL6-3544H
• Description: ARL6, also known ADP-ribosylation factor-like protein 6, belongs to the ARF family of GTP-binding proteins. This protein is known to play essential roles in modulating membrane trafficking and cytoskeletal functions. Mutation in ARL6 causes Bardet-Biedl syndrome (BBS3). BBS is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnor-malities and developmental delay.
• Source: E. coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.2M NaCl, 5mM DTT
• Molecular weight: 23.2 kDa (206aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPT IGFSIEKFKS SSLSFTVFDM SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKH RRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ IQTVKT
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: ARL6 ADP-ribosylation factor-like 6 [ Homo sapiens ]
• Synonyms: ADP-ribosylation factor-like 6; BBS3; OTTHUMP00000214308; ARL6; RP55; OTTHUMP00000214309; MGC32934; OTTHUMP00000214310; bardet-Biedl syndrome 3 protein ADP-ribosylation factor-like protein 6
• Gene ID: 84100
• mRNA Refseq: NM_032146
• Protein Refseq: NP_115522
• MIM: 608845
• UniProt ID: Q9H0F7
• Chromosome Location: 3q11.2
• Function: GTP binding; metal ion binding; nucleotide binding; protein binding