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Recombinant Human Cofilin 1 (non-muscle), His-tagged
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Cat. No. : | CFL1-1580H |
Product Overview : | Recombinant full-length human CFL1 was expressed in E. coli cells using an N-terminal His tag. |
Description : | Cofilin 1 (non-muscle), also known as CFL1, is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. CFL1 processed proteins are most probably produced by HIV-1 protease digestion. |
Applications : | Western Blot |
Molecular Weight : | 23 kDa |
Expression System : | E. coli |
Species : | Human |
Form : | Recombinant protein stored in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 2 mM DTT, 25 % glycerol. |
Purity : | > 95 % |
Concentration : | 0.2 ug/ul |
Sequences : | Full-lengt h |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Axon guidance; CDC42 signaling events; CXCR4-mediated signaling events; Fc gamma R-mediated phagocytosis; Formation of Platelet plug; G13 Signaling Pathway; Hemostasis; Pertussis; Platelet Activation; RAC1 signaling pathway; Regulation of Actin Cytoskeleton; RhoA signaling pathway; Sema3A PAK dependent Axon repulsion; Semaphorin interactions |
PDB rendering based on 1q8g. : |
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Gene Name : | CFL1 cofilin 1 (non-muscle) [ Homo sapiens ] |
Official Symbol : | CFL1 |
Synonyms : | CFL1; cofilin 1 (non-muscle); CFL; cofilin-1; p18; OTTHUMP00000233679; OTTHUMP00000233680; OTTHUMP00000233681; OTTHUMP00000233682; OTTHUMP00000233740; OTTHUMP00000233741; OTTHUMP00000233742; 18 kDa phosphoprotein; Cofilin-1, non-muscle isoform; Cofilin-1 |
Gene ID : | 1072 |
mRNA Refseq : | NM_005507 |
Protein Refseq : | NP_005498 |
MIM : | 601442 |
UniProt ID : | P23528 |
Chromosome Location : | 11q13 |
Function : | actin binding; protein binding |
◆ Recombinant Protein
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CFL1-1172H | Recombinant Human CFL1 Protein, GST-Tagged | +Inquiry |
CFL1-366H | Recombinant Human CFL1, His tagged | +Inquiry |
CFL1-3350M | Recombinant Mouse CFL1 Protein | +Inquiry |
CFL1-26844TH | Recombinant Human CFL1, His-tagged | +Inquiry |
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◆ Lysates
CFL1-7555HCL | Recombinant Human CFL1 293 Cell Lysate | +Inquiry |
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