Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Doublecortin-like Kinase 1, GST-tagged

Cat.No. : DCLK1-1009H
Product Overview : Full-length recombinant human DCLK1 was expressed by baculovirus in Sf9 cells using an N-terminal GST tag.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Cat. No. : DCLK1-1009H
Description : DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCLK1 is a microtubule-associated kinase that can undergo autophosphorylation. DCLK1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCLK1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.
Applications : Kinase Assay; Western Blot
Molecular Weight : 110 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
Specific Activity : 3.4 nmol/min/mg
Purity : > 85 %
Concentration : 0.1 ug/ul
Sequences : Full length
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : DCLK1 doublecortin-like kinase 1 [ Homo sapiens ]
Official Symbol : DCLK1
Synonyms : DCLK1; doublecortin-like kinase 1; CL1; DCLK; CLICK1; DCDC3A; DCAMKL1; KIAA0369; serine/threonine-protein kinase DCLK1; OTTHUMP00000018250; OTTHUMP00000018251; OTTHUMP00000018252; doublecortin and CaM kinase-like 1; doublecortin-like and CAM kinase-like 1; doublecortin domain-containing protein 3A; EC=2.7.11.1
Gene ID : 9201
mRNA Refseq : NM_004734
Protein Refseq : NP_004725
MIM : 604742
UniProt ID : O15075
Chromosome Location : 13q13.3
Function : ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; receptor signaling protein activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All DCLK1 Products

Required fields are marked with *

My Review for All DCLK1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends