"GSG2" Related Products

Recombinant Human Germ Cell Associated 2 (haspin), GST-tagged

Cat. No.: GSG2-1586H
Product Overview: Recombinant human GSG2 (470-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: GSG2 is a protein kinase that regulates chromosome and spindle function during mitosis and meiosis. GSG2 expression is detected in fetal liver, skin, kidney, small intestine and in all proliferating cells. GSG2 phosphorylates H3 thr3 (H3T3ph) in human cell lines and depletion ofGSG2 by RNA interference reveals that GSG2 is required for H3 thr3 phosphorylation in mitotic cells.
Applications: Kinase Assay; Western Blot
Molecular Weight: 64 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: >75%
Concentration: 0.1 ug/ul
Specific Activity: 18 nmol/min/mg
Sequences: 470-end
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: GSG2 germ cell associated 2 (haspin) [ Homo sapiens ]
Official Symbol: GSG2
Synonyms: GSG2; germ cell associated 2 (haspin); HASPIN; serine/threonine-protein kinase haspin; H-haspin; OTTHUMP00000115873; germ cell-specific gene 2 protein; haploid germ cell-specific nuclear protein kinase
Gene ID: 83903
mRNA Refseq: NM_031965
Protein Refseq: NP_114171
MIM: 609240
UniProt ID: Q8TF76
Chromosome Location: 17p13
Function: ATP binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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