Recombinant Human Cyclin G1, His-tagged
Cat.No. : | CCNG1-1331H |
Product Overview : | Recombinant human CCNG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
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Cat. No. : | CCNG1-1331H |
Description : | CCNG1, also known as cyclin-G1, is a member of the cyclin family and contains the cyclin box. It may play a role in growth regulation and be associated with G2/M phase arrest in response to DNA damage. It may be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 5 mM DTT, 50% glycerol, 0.2 M NaCl. |
Molecular Weight : | 36.2 kDa (315 aa) confirmed by MALDI-TOF |
Purity : | > 85 % by SDS-PAGE |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MIEVLTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS CFYLAVKSIE EERNVPLATD LIRISQYRFT VSDLMRMEKI VLEKVCWKVK ATTAFQFLQL YYSLLQENLP LERRNSINFE RLEAQLKACH CRIIFSKAKP SVLALSIIAL EIQAQKCVEL TEGIECLQKH SKINGRDLTF WQELVSKCLT EYSSNKCSKP NVQKLKWIVS GRTARQLKHS YYRITHLPTI PEMVP |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Direct p53 effectors; p53 pathway; p53 signaling pathway |
Gene Name : | CCNG1 cyclin G1 [ Homo sapiens ] |
Official Symbol : | CCNG1 |
Synonyms : | CCNG1; cyclin G1; CCNG; OTTHUMP00000223693; OTTHUMP00000223697; OTTHUMP00000223691; OTTHUMP00000223692; OTTHUMP00000223690; cyclin-G; Cyclin-G; CYCG1 |
Gene ID : | 900 |
mRNA Refseq : | NM_004060 |
Protein Refseq : | NP_004051 |
MIM : | 601578 |
UniProt ID : | P51959 |
Chromosome Location : | 5q32-q34 |
Function : | Protein domain specific binding |
Products Types
◆ Recombinant Protein | ||
CCNG1-0669H | Recombinant Human CCNG1 Protein, GST-Tagged | +Inquiry |
CCNG1-1408M | Recombinant Mouse CCNG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCNG1-882R | Recombinant Rat CCNG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCNG1-825H | Recombinant Human CCNG1 Protein, GST-His-tagged | +Inquiry |
CCNG1-2995M | Recombinant Mouse CCNG1 Protein | +Inquiry |
◆ Lysates | ||
CCNG1-7707HCL | Recombinant Human CCNG1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTargeting CCNG1 in cancer therapy could help control tumor growth by affecting cell cycle dynamics.
Dysregulated CCNG1 expression is linked with the advancement of various cancers due to its role in cell cycle control.
CCNG1, as a cyclin, regulates the cell cycle, particularly the transition between phases.
It contributes to cellular senescence by influencing cell cycle arrest mechanisms.
Mutations in CCNG1 can lead to aberrant cell cycle progression, potentially resulting in cancer.
CCNG1 works in tandem with other cell cycle proteins and signaling pathways to regulate cell division.
CCNG1 plays a role in DNA damage response, helping to maintain genomic stability.
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