Recombinant Human Defensin, Beta 1
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| Cat. No. : | DEFB1-035H |
| Product Overview : | Recombinant human DEFB1 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
| Description : | Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. |
| Source : | Human |
| Host : | E. coli |
| Form : | Supplied as a lyophilized powder. |
| Purity : | >98% pure by SDS PAGE and HPLC |
| Sequence : | Region of BD1 protein corresponding to amino acids DHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK. |
| Molecular Mass : | 3.9 kDa |
| Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
| Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
| Bioactivity : | Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100.0-1000.0 ng/ml. |
| Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
| PDBrendering based on 1e4s. : |
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| Gene Name : | DEFB1 defensin, beta 1 [ Homo sapiens ] |
| Official Symbol : | DEFB1 |
| Synonyms : | DEFB1; BD1; DEFB101; HBD1; hBD-1; beta-defensin-1; defensin beta 1; MGC51822; Beta-defensin 1 precursor; BD-1; DEFB1 |
| Gene ID : | 1672 |
| mRNA Refseq : | NM_005218 |
| Protein Refseq : | NP_005209 |
| MIM : | 602056 |
| UniProt ID : | P60022 |
| Chromosome Location : | 8p23.1 |
◆ Recombinant Protein
| DEFB1-2521H | Recombinant Human DEFB1 Protein, GST-tagged | +Inquiry |
| DEFB1-455H | Recombinant Human DEFB1 Protein, MYC/DDK-tagged | +Inquiry |
| DEFB1-1227R | Recombinant Rhesus monkey DEFB1 Protein, His-tagged | +Inquiry |
| Defb1-596R | Recombinant Rat Defb1 protein | +Inquiry |
| Defb1-6877M | Recombinant Mouse Defb1 protein, His & S-tagged | +Inquiry |
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◆ Lysates
| DEFB1-6989HCL | Recombinant Human DEFB1 293 Cell Lysate | +Inquiry |
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DEFB1DEFB103ADEFB104ADEFB4DEFB4ADEFB4BDEFB103BDEFB104BDEFB106ADEFB105ADEFB131DEFB109DEFB110DEFB108BDEFB116DEFB118DEFB119DEFB125DEFB121DEFB132DEFB129DEFB133DEFB134Defb3Defb11Defb19Defb2Defb20Defb21Defb22Defb23Defb24Defb25Defb26Defb27Defb28Defb29Defb30Defb33Defb34Defb51Defb52Defb6Defb7Defb8Defb9Defb10Defb35Defb36Defb37Defb38Defb39Defb40Defb41Defb42Defb43Defb44Defb45Defb46Defb47Defb48Defb49Defb5Defb50DEFB107ADEFB123DEFB124DEFB126DEFB127DEFB128DEFB130
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