Recombinant Human Actin Related Protein 2/3 Complex, Subunit 5, 16kDa, His-tagged ARPC5-4975H

Recombinant Human Actin Related Protein 2/3 Complex, Subunit 5, 16kDa, His-tagged

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Recombinant Human Actin Related Protein 2/3 Complex, Subunit 5, 16kDa, His-tagged

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Cat. No. : ARPC5-4975H
Product Overview : Recombinant human ARPC5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Description : p16-ARC, also known as ARPC5, is a 151 amino acid subunit of the Arp2/3 complex. Thought to play a role in maintaining the integrity of Arp2/3, ARPC5 is a substrate for MAPKAPK-2 which, through phosphorylation of ARPC5, may participate in Arp2/3 regulatory functions and remodeling of the Actin cytoskeleton. Two isoforms of ARPC5 exist due to alternative splicing events.
Concentration : 0.5 mg/ml
Source : Human
Host : E.coli
Form : Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 50% glycerol and 0.1M NaCl.
Purity : > 90% by SDS - PAGE
Sequence : 1-151 amino acids: MGSSHHHHHH SSGLVPRGSH MSKNTVSSAR FRKVDVDEYD ENKFVDEEDG GDGQAGPDEG EVDSCLRQGN MTAALQAALK NPPINTKSQA VKDRAGSIVL KVLISFKAND IEKAVQSLDK NGVDLLMKYI YKGFESPSDN SSAMLLQWHE KALAAGGVGS IVRVLTARKT V
Molecular Mass : 18.4 kDa (171aa), confirmed by MALDI-TOF
Applications : SDS-PAGE
Storage : Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
PDBrendering based on 1k8k. :

Gene Name : ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa [ Homo sapiens ]
Official Symbol : ARPC5
Synonyms : ARPC5; ARC16; p16-Arc; MGC88523; dJ127C7.3; actin related protein 2/3 complex, subunit 5, 16kDa; actin-related protein 2/3 complex subunit 5; OTTHUMP00000033266; OTTHUMP00000033267; OTTHUMP00000038626; arp2/3 complex 16 kDa subunit; Arp2/3 protein complex subunit p16; p16-ARC
Gene ID : 10092
mRNA Refseq : NM_005717
Protein Refseq : NP_005708
MIM : 604227
UniProt ID : O15511
Chromosome Location : 1q25.3
Pathway : B Cell Receptor Signaling Pathway; CDC42 signaling events; ErbB1 downstream signaling; Fc gamma R-mediated phagocytosis; Pathogenic Escherichia coli infection; RAC1 signaling pathway; Regulation of Actin Cytoskeleton; Salmonella infection; Shigellosis
Function : actin binding; protein binding; structural constituent of cytoskeleton

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