"IFNA1" Related Products


Recombinant Human Interferon Alpha1b

Cat. No.: IFNA1-07H
Product Overview: Recombinant Human Interferon-α1b produced inE.coliis a single non-glycosylated polypeptide chain containing 166 amino acids and having a molecular mass of approximately 19 kDa
Description: At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
Purity: >96% by SDS-PAGE and HPLC analyses.
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation: Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in PBS, pH 7.4.
Specific Activity: Fully biologically active when compared to standard. The specific activity as determined in a viral resistance assay was found to be no less than 1.0 x 108IU/mg.
Endotoxin: Less than 1EU/μg of rHuIFN-α1b as determined by LAL method.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
Storage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Gene Name: IFNA1
Synonyms: interferon, alpha 1; IFNA@; IFL; IFN; IFN-ALPHA; IFNA13; IFN-alpha 1b; interferon alpha 1b; IFNA1_HUMAN; Interferon alpha-1/13 [Precursor]; Interferon alpha-D; LeIF D; MGC138207; MGC138505; MGC138507; OTTHUMP00000045110; IFNA1
Gene ID: 3439
mRNA Refseq: NM_024013
Protein Refseq: NP_076918
MIM: 147660
UniProt ID: P01562
Chromosome Location: 9p22
Pathway: Antigen processing and presentation; Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; Regulation of autophagy; Toll-like receptor signaling pathway.

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