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Recombinant Human SEMA3C, His-tagged

Cat.No. : SEMA3C-7777H
Product Overview : Recombinant Human Semaphorin 3C is produced by our mammalian cells expression system in HEK293. The target protein is expressed with sequence (Gly21Ser738) of Human SEMA3C fused with a polyhistidine tag at the Cterminus.
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Description : Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be upregulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N terminal Sema domain, a cysteine knot, a furinetype cleavage site, an Iglike domain, and a Cterminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary and prostate, expressed lowly in the other organs, including the brain.
Source : HEK293 Cells
Species : Human
Tag : His
Form : Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.4
AA Sequence : GSSQPQARVY LTFDELRETK TSEYFSLSHH PLDYRILLMD EDQDRIYVGS KDHILSLNIN NISQEALSV FWPASTIKVE ECKMAGKDPT HGCGNFVRVI QTFNRTHLYV CGSGAFSPVC T YLNRGRRS EDQVFMIDSK CESGKGRCSF NPNVNTVSVM INEELFSGMY IDFMGTDAAI FR SLTKRNA VRTDQHNSKW LSEPMFVDAH VIPDGTDPND AKVYFFFKEK LTDNNRSTKQ IHS MIARIC PNDTGGLRSL
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Notes : For research use only.
Storage : Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.
Gene Name : SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C [ Homo sapiens ]
Official Symbol : SEMA3C
Synonyms : SEMA3C; SEMAE, SemE; sema E; semaphorin E
Gene ID : 10512
mRNA Refseq : NM_006379.3
Protein Refseq : NP_006370.1
MIM : 602645
UniProt ID : Q99985
Chromosome Location : 7q21-q31
Pathway : Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem
Function : receptor activity; semaphorin receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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