Recombinant Human CDC73, His-tagged
Cat.No. : | CDC73-7927H |
Product Overview : | Recombinant Human Parafibromin is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2Glu260) of Human CDC73 fused with a 6His tag at the Nterminus. |
- Specification
- Gene Information
- Related Products
Description : | Parafibromin is expressed in the adrenal and parathyroid glands, kidney, and heart. As a tumor supressor, Parafibromin may be involved in transcriptional and posttranscriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex and interacts with a Set1like complex that has histone methyltransferase activity and methylates histone H3. Defects in Parafibromin can cause hyperparathyroidismjaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.4 |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Notes : | For research use only. |
Storage : | Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months. |
Gene Name : | CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | CDC73 |
Synonyms : | CDC73; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); C1orf28, chromosome 1 open reading frame 28 , HRPT2, hyperparathyroidism 2 (with jaw tumor); parafibromin; hyperparathyroidism 2 protein; cell division cycle protein 73 homolog; HYX; HPTJT; HRPT2; C1orf28; FLJ23316; |
Gene ID : | 79577 |
mRNA Refseq : | NM_024529 |
Protein Refseq : | NP_078805 |
MIM : | 607393 |
UniProt ID : | Q6P1J9 |
Chromosome Location : | 1q25 |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
CDC73-1494M | Recombinant Mouse CDC73 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC73-717H | Recombinant Human CDC73 Protein, His-tagged | +Inquiry |
CDC73-941R | Recombinant Rat CDC73 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC73-0959H | Recombinant Human CDC73 Protein, GST-Tagged | +Inquiry |
CDC73-597R | Recombinant Rhesus Macaque CDC73 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CDC73-7645HCL | Recombinant Human CDC73 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket