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Native Human Brain Natriuretic Peptide 32

Cat.No.: NPPB-8050H
Product Overview: Human Brain Natriuretic Peptide 32 was purified from Human Brain.
Description: Brain Natriuretic Peptide (BNP-32) (also known as B-type natriuretic peptide or "GC-B") is a 32-amino-acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes (heart muscles cells) in the ventricles. At the time of release, a co-secreted 76 amino acid n-terminal fragment (NT-proBNP) is also released with B-type natriuretic peptide BNP. B-type natriuretic peptide BNP binds to and activates NPRA in a similar fashion to atrial natriuretic peptide but with 10-fold lower affinity. The biological half-life of BNP however, is twice as long as that of ANP. Both ANP and B-type natriuretic peptide BNP have limited ability to bind and activate NPRB.
Source: Human Brain
Species: Human
Form: Lyophilized, Acetate Salt
Purity: >99% pure
Storage: -20 °C
Gene Name: NPPB natriuretic peptide B [ Homo sapiens ]
Official Symbol: NPPB
Synonyms: NPPB; natriuretic peptide B; natriuretic peptide precursor B; natriuretic peptides B; natriuretic protein; brain type natriuretic peptide; gamma-brain natriuretic peptide; BNP;
Gene ID: 4879
mRNA Refseq: NM_002521
Protein Refseq: NP_002512
MIM: 600295
UniProt ID: P16860
Chromosome Location: 1p36.2
Pathway: MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem;
Function: diuretic hormone activity; hormone activity; peptide hormone receptor binding; receptor binding; receptor binding;

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