Recombinant Human ANKRD54, His-tagged

• Cat.No.: ANKRD54-7611H
• Product Overview: Recombinant human ANKRD54 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: ANKRD54, also known as LIAR, contains 4 ANK repeats. This protein plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. This protein interacts (via ankyrin repeat region) with LYN (via SH3-domain) in an activation-independent status of LYN. It forms a multiprotein complex with LYN and HCLS1. ANKRD54 also interacts with TSN2, VAV1, DBNL AND LASP1.?
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
• Molecular Mass: 34.9kDa (323aa)
• Protein length: 1-300aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAAAGD ADDEPRSGHS SSEGECAVAP EPLTDAEGLF SFADFGSALG GGGAGLSGRA SGGAQSPLRY LHVLWQQDAE PRDELRCKIP AGRLRRAARP HRRLGPTGKE VHALKRLRDS ANANDVETVQ QLLEDGADPC AADDKGRTAL HFASCNGNDQ IVQLLLDHGA DPNQRDGLGN TPLHLAACTN HVPVITTLLR GGARVDALDR AGRTPLHLAK SKLNILQEGH AQCLEAVRLE VKQIIHMLRE YLERLGQHEQ RERLDDLCTR LQMTSTKEQV DEVTDLLASF TSLSLQMQSM EKR
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml?

Gene Information

• Gene Name: ANKRD54 ankyrin repeat domain 54 [ Homo sapiens ]
• Official Symbol: ANKRD54
• Synonyms: ANKRD54; ankyrin repeat domain 54; ankyrin repeat domain-containing protein 54; LIAR
• Gene ID: 129138
• mRNA Refseq: NM_138797
• Protein Refseq: NP_620152
• MIM: 613383
• UniProt ID: Q6NXT1
• Chromosome Location: 22q13.1
• Function: protein complex binding; protein kinase regulator activity