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Recombinant Human ZMAT3, His-tagged

Cat.No. : ZMAT3-15896H
Product Overview : Recombinant human ZMAT3 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
  • Specification
  • Gene Information
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Description : ZMAT3 is a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Molecular Mass : 34.4 kDa (312aa) confirmed by MALDI-TOF
Protein length : 1-289aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMILLQHA VLPPPKQPSP SPPMSVATRS TGTLQLPPQK PFGQEASLPL AGEEELSKGG EQDCALEELC KPLYCKLCNV TLNSAQQAQA HYQGKNHGKK LRNYYAANSC PPPARMSNVV EPAATPVVPV PPQMGSFKPG GRVILATEND YCKLCDASFS SPAVAQAHYQ GKNHAKRLRL AEAQSNSFSE SSELGQRRAR KEGNEFKMMP NRRNMYTVQN NSAGPYFNPR SRQRIPRDLA MCVTPSGQFY CSMCNVGAGE EMEFRQHLES KQHKSKVSEQ RYRNEMENLG YV
Purity : >85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : ZMAT3 zinc finger, matrin-type 3 [ Homo sapiens ]
Official Symbol : ZMAT3
Synonyms : ZMAT3; zinc finger, matrin-type 3; zinc finger matrin-type protein 3; FLJ12296; MGC10613; PAG608; WIG 1; WIG1; WIG-1/PAG608 protein; zinc finger protein WIG1; zinc finger protein WIG-1; zinc finger, matrin type 3; p53 target zinc finger protein; p53-activated gene 608 protein; WIG-1; FLJ31683;
Gene ID : 64393
mRNA Refseq : NM_022470
Protein Refseq : NP_071915
MIM : 606452
UniProt ID : Q9HA38
Chromosome Location : 3q26.32
Pathway : p53 signaling pathway, organism-specific biosystem; p53 signaling pathway, conserved biosystem;
Function : RNA binding; metal ion binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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